Lili Zhang Selected Research

Alzheimer Disease (Alzheimer's Disease)

8/2024	Ferroptosis mechanism and Alzheimer's disease.
1/2020	MK-8719, a Novel and Selective O-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy.
11/2018	Label-free imaging of amyloid plaques in Alzheimer's disease with stimulated Raman scattering microscopy.
12/2016	Design and synthesis of water soluble β-aminosulfone analogues of SCH 900229 as γ-secretase inhibitors.
11/2016	Substituted 4-morpholine N-arylsulfonamides as γ-secretase inhibitors.
1/2016	Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography.
11/2015	Discovery of a Novel, Potent Spirocyclic Series of γ-Secretase Inhibitors.
3/2015	Analysis of tau post-translational modifications in rTg4510 mice, a model of tau pathology.
2/2013	Structure activity relationship studies of tricyclic bispyran sulfone γ-secretase inhibitors.
1/2013	The discovery of fused oxadiazepines as gamma secretase modulators for treatment of Alzheimer's disease.

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Lili Zhang Research Topics

Disease

135	Neoplasms (Cancer) 05/2024 - 10/2003
60	Inflammation (Inflammations) 04/2024 - 09/2009
39	Infections 04/2024 - 07/2007
32	Body Weight (Weight, Body) 01/2023 - 03/2009
31	Fetal Growth Retardation (Intrauterine Growth Retardation) 04/2024 - 07/2012
26	Alzheimer Disease (Alzheimer's Disease) 08/2024 - 08/2003
24	Breast Neoplasms (Breast Cancer) 01/2024 - 02/2012
21	Neoplasm Metastasis (Metastasis) 02/2023 - 09/2015
20	Insulin Resistance 12/2023 - 06/2008
19	Carcinogenesis 01/2024 - 08/2008
19	Birth Weight (Birth Weights) 04/2022 - 01/2015
18	Atherosclerosis 05/2024 - 01/2017
18	Type 2 Diabetes Mellitus (MODY) 02/2024 - 11/2011
18	Fibrosis (Cirrhosis) 04/2023 - 06/2011
15	COVID-19 01/2024 - 11/2020
13	Cardiovascular Diseases (Cardiovascular Disease) 02/2024 - 01/2017
13	Mitochondrial Diseases (Mitochondrial Disease) 08/2022 - 08/2014
13	Hepatocellular Carcinoma (Hepatoma) 05/2022 - 01/2014
12	Heart Failure 02/2024 - 01/2017
12	Stroke (Strokes) 01/2024 - 05/2012
12	Schizophrenia (Dementia Praecox) 12/2021 - 12/2014
11	Myocardial Infarction 01/2023 - 04/2007
11	Myocarditis (Carditis) 12/2022 - 07/2009
10	Lung Neoplasms (Lung Cancer) 05/2024 - 01/2012
10	Obesity 04/2024 - 10/2016
10	Liver Cirrhosis (Hepatic Cirrhosis) 01/2024 - 08/2012
10	Prostatic Neoplasms (Prostate Cancer) 11/2023 - 08/2008
10	Hypertension (High Blood Pressure) 10/2023 - 04/2010
9	Endometrial Neoplasms (Endometrial Cancer) 07/2023 - 03/2009
9	Hypoxia (Hypoxemia) 06/2023 - 08/2015
8	Infarction (Infarctions) 04/2024 - 05/2012
8	Ischemia 10/2023 - 04/2007
8	Stomach Neoplasms (Stomach Cancer) 01/2023 - 09/2011
7	Diabetes Mellitus 05/2024 - 03/2009
7	Cardiotoxicity 01/2023 - 01/2019
7	Ischemic Stroke 05/2020 - 01/2012
6	Diabetic Nephropathies (Diabetic Nephropathy) 05/2024 - 01/2010
6	Colorectal Neoplasms (Colorectal Cancer) 03/2024 - 11/2019
6	Dehydration (Water Stress) 02/2024 - 01/2014
6	Non-alcoholic Fatty Liver Disease 02/2024 - 05/2013
6	Hypersensitivity (Allergy) 01/2024 - 01/2013
6	Pneumonia (Pneumonitis) 12/2023 - 01/2014
6	Coronary Artery Disease (Coronary Atherosclerosis) 10/2023 - 01/2018
6	Coronary Disease (Coronary Heart Disease) 01/2023 - 01/2015
6	Pain (Aches) 01/2023 - 04/2009
6	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2023 - 10/2011

Drug/Important Bio-Agent (IBA)

79	Proteins (Proteins, Gene)FDA Link 02/2024 - 03/2004
37	Biomarkers (Surrogate Marker)IBA 05/2024 - 02/2007
32	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 03/2009
25	LipidsIBA 01/2024 - 03/2009
22	Messenger RNA (mRNA)IBA 01/2024 - 02/2007
20	CytokinesIBA 11/2023 - 07/2009
18	EnzymesIBA 12/2023 - 08/2003
17	Immune Checkpoint InhibitorsIBA 01/2024 - 06/2019
16	AntioxidantsIBA 01/2023 - 09/2012
16	CurcuminIBA 06/2022 - 02/2014
15	Therapeutic UsesIBA 06/2023 - 01/2016
14	MicroRNAs (MicroRNA)IBA 04/2023 - 11/2015
13	Blood Glucose (Blood Sugar)IBA 04/2024 - 03/2009
13	Insulin (Novolin)FDA Link 12/2023 - 06/2008
13	LipopolysaccharidesIBA 11/2023 - 08/2014
12	VaccinesIBA 05/2023 - 12/2012
12	ResveratrolIBA 01/2021 - 01/2017
11	Peptides (Polypeptides)IBA 01/2024 - 08/2003
11	Interleukin-6 (Interleukin 6)IBA 11/2023 - 09/2014
11	Triglycerides (Triacylglycerol)IBA 11/2023 - 06/2008
11	DNA (Deoxyribonucleic Acid)IBA 05/2022 - 02/2010
10	CalciumIBA 02/2024 - 03/2009
10	CholesterolIBA 11/2023 - 03/2009
10	RNA (Ribonucleic Acid)IBA 10/2023 - 01/2017
10	Cisplatin (Platino)FDA LinkGeneric 06/2023 - 07/2007
9	CollagenIBA 01/2023 - 11/2013
9	Indicators and Reagents (Reagents)IBA 01/2022 - 10/2012
9	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 12/2016 - 08/2003
8	Apolipoproteins E (ApoE)IBA 05/2024 - 01/2012
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2023 - 03/2009
8	Small Interfering RNA (siRNA)IBA 06/2023 - 08/2008
8	AntigensIBA 12/2022 - 10/2015
8	Paliperidone Palmitate FDA Link 12/2021 - 01/2017
7	Antiviral Agents (Antivirals)IBA 01/2024 - 11/2012
7	salicylhydroxamic acid (SHAM)IBA 01/2024 - 02/2015
7	Anti-Bacterial Agents (Antibiotics)IBA 01/2023 - 11/2010
7	Nonesterified Fatty Acids (NEFA)IBA 12/2022 - 06/2008
7	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 07/2022 - 07/2007
7	Antipsychotic Agents (Antipsychotics)IBA 12/2021 - 11/2016
7	Gamma Secretase Inhibitors and ModulatorsIBA 01/2013 - 12/2006
6	Amino Acids FDA Link 02/2024 - 10/2012
6	AntibodiesIBA 12/2023 - 01/2010
6	Oxygen (Dioxygen)IBA 10/2023 - 05/2012
6	HDL CholesterolIBA 04/2023 - 03/2009
6	Transcription Factors (Transcription Factor)IBA 01/2023 - 01/2014
6	Hormones (Hormone)IBA 01/2023 - 06/2011
6	LigandsIBA 08/2022 - 09/2011

Therapy/Procedure

78	Therapeutics 08/2024 - 11/2011
23	Drug Therapy (Chemotherapy) 05/2024 - 03/2011
9	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2024 - 01/2013
8	Immunotherapy 01/2024 - 12/2016
8	Precision Medicine 12/2023 - 01/2016
8	Radiotherapy 01/2023 - 01/2017
6	Cardiopulmonary Resuscitation (CPR) 01/2023 - 03/2019